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          賽諾菲CEO韓保羅:企業級AI轉型將在2026年重塑制藥行業

          Paul Hudson
          2026-02-12

          AI驅動的工具也在重塑研發的經濟邏輯。

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          賽諾菲首席執行官韓保羅。圖片來源:courtesy of Sanofi

          在今年的達沃斯世界經濟論壇上,AI成為討論的核心議題。越來越多的人已經認識到,它對創新與增長所產生的影響。我相信,在未來數月,各行各業的公司都會證明:AI并非一時的投機熱潮,而是持久的變革引擎,它正在從根本上重塑我們的工作方式。

          在賽諾菲(Sanofi),AI已從早期實驗階段,轉變為基礎設施中的關鍵組成部分。如今,它支持我們的研發決策、供應鏈與制造流程,更重要的是,支撐我們發現與開發藥物的方式。任何成功將AI落地的企業,都會面臨技能缺口與不確定性等挑戰,但解決之道在于將AI深度嵌入團隊與系統之中,使其成為持續生產力與創新的關鍵可靠來源。

          展望2026年及以后,關鍵在于企業級規模的落地實施,即從AI實驗探索,轉向將其作為企業運作的核心。這將是AI投機的終結點,也將是AI成為增長根本驅動力的開始。隨著越來越多組織進入這一階段,關于泡沫的討論,已經讓位于AI在多個領域中展現的長期價值證據——包括由AI發現的新藥、優化供應鏈與制造體系,以及依托新技術實現的預防性醫療。

          AI驅動藥物研發的新時代

          根據波士頓咨詢公司(Boston Consulting Group)的一份報告,生成式AI有潛力將早期藥物研發周期縮短25%以上。

          在賽諾菲,我們已經看到這一趨勢帶來的顯著成果。通過將機器學習與數據整合能力結合實驗室研究,我們在一年內發現了10個全新的藥物靶點。AI已不再只是輔助研發工作,而是在主動塑造決策流程。我們在召開藥物開發委員會會議時,會先由AI智能體評估一款候選藥物是否應進入下一臨床試驗階段。關鍵在于,這個智能體并非簡單給出“是”或“否”的答案,而是對每一項決策進行完整的情境分析。它會將該資產的前景與其他在研項目進行對比,并評估其相對于賽諾菲其他資本用途的機會成本。這是一個有力的案例,說明AI讓藥物研發不僅更快速,而且更智能。

          這種轉型并不僅限于實驗室。AI還在解決藥物研發中最頑固的難題之一:臨床試驗招募。AI驅動的患者招募工具,可將臨床試驗入組率提升65%。借助AI,我們能夠通過掃描電子病歷、臨床記錄與化驗結果,自動篩選符合條件的患者,從而更精準地匹配復雜的試驗標準。同時,我們還能實時判斷某個臨床試驗中心的入組進展是否低于預期,并將資源轉向進展更快的中心。過去需要數月才能完成招募的試驗,如今可在數天或數周內找到合適人選。

          除了加速靶點發現與臨床試驗招募流程,AI驅動的工具也在重塑研發的經濟邏輯。通過加快早期藥物發現并生成科學洞見,AI有望將相關成本降低約50%。這些變化將重新定義哪些類型的藥物具備商業可行性。未來一年,尤其是在精準醫療領域,我們可以期待關鍵突破變得更具規模化和可及性。近期多項研究指出,在AI、多組學技術以及前所未有的數據基礎設施支持下,精準醫療正從高度定制化靶向治療,轉向面向大規模人群的普惠醫療模式。

          構建下一代供應鏈與制造體系

          AI識別供應鏈脆弱性的能力幾乎無可匹敵。借助更高水平的可視化與實時追蹤能力,AI系統能夠以前所未有的方式洞察庫存狀況與產品流向。

          在賽諾菲,AI驅動的供應鏈管理已幫助公司規避了3億美元的收入風險,并提前預測到80%的低庫存風險。通過擴大數據獲取范圍、提升跨部門透明度,企業能夠及時作出更明智的決策。其影響是切實可見的:已有68%的供應鏈企業整合了AI以增強可追溯性與透明度,運營效率因此提升22%。未來幾年,隨著 AI進一步融入全球供應網絡,這些效益還將持續加速顯現。

          除了提升供應鏈的可視化與預測能力,AI也正在重塑藥品制造方式。它為制造流程提供端到端支持,包括提高效率、改善產品質量與安全性,以及通過實時監測確保穩定、可靠的產出。根據麥肯錫(McKinsey & Company)的分析,AI驅動的數據分析能夠顯著提高產出率,不僅有助于患者更快獲得關鍵藥物,也能提升制造運營的成本效率與可持續性。

          推進預防性與預測性醫療

          預防醫學的下一個前沿是依托遠程患者監測與數字化工具,實現早期干預。一項涵蓋 1,100余例患者診療案例的研究發現,遠程患者監測可將住院率降低近60%。在慢性病管理領域,可穿戴設備、癥狀追蹤應用以及環境傳感器的結合,正展現出變革性潛力。針對慢性阻塞性肺?。–OPD)患者,一項整合上述工具的數字化項目在預測病情加重方面實現了94%的敏感度與90.4%的特異度,使臨床醫生能夠在危機發生前介入。這類整合型數字治療模式,正在減少脆弱人群的急診就診與住院率。隨著AI加速制藥與醫療行業的進程,我們在更早階段進行發現、預測與干預的能力也將持續提升。

          預防醫學的未來,將由疫苗、治療手段、數據與智能監測的融合所定義。通過將科學創新與AI驅動的洞見相結合,我們有機會推動醫療模式從“被動治療”轉向“主動、持續的防護”。這將帶來更好的治療效果、更低的成本,并最終大規模改變患者生活。

          我們正步入一個由AI驅動企業各項職能的新時代。2026年,制藥行業的AI轉型有望進一步提速,我們將持續推進改變患者命運的藥物研發。隨著AI能力的不斷擴展,我們已經看到討論的重點已經從對“泡沫”的擔憂,轉向了對企業驅動的長期價值的關注。最終留下的,可能不是炒作,而是持續增長與深層變革。(財富中文網)

          本文作者韓保羅自2019年9月起擔任賽諾菲首席執行官。此前,他于2016年至2019年出任諾華制藥首席執行官。在加入諾華之前,曾就職于阿斯利康,擔任多個高管職務,包括阿斯利康美國總裁及北美區執行副總裁。職業生涯早期,他在葛蘭素史克英國公司以及賽諾菲-信達博英國公司擔任銷售和市場營銷崗位。

          Fortune.com上發表的評論文章中表達的觀點,僅代表作者本人的觀點,不代表《財富》雜志的觀點和立場。

          譯者:劉進龍

          審校:汪皓

          在今年的達沃斯世界經濟論壇上,AI成為討論的核心議題。越來越多的人已經認識到,它對創新與增長所產生的影響。我相信,在未來數月,各行各業的公司都會證明:AI并非一時的投機熱潮,而是持久的變革引擎,它正在從根本上重塑我們的工作方式。

          在賽諾菲(Sanofi),AI已從早期實驗階段,轉變為基礎設施中的關鍵組成部分。如今,它支持我們的研發決策、供應鏈與制造流程,更重要的是,支撐我們發現與開發藥物的方式。任何成功將AI落地的企業,都會面臨技能缺口與不確定性等挑戰,但解決之道在于將AI深度嵌入團隊與系統之中,使其成為持續生產力與創新的關鍵可靠來源。

          展望2026年及以后,關鍵在于企業級規模的落地實施,即從AI實驗探索,轉向將其作為企業運作的核心。這將是AI投機的終結點,也將是AI成為增長根本驅動力的開始。隨著越來越多組織進入這一階段,關于泡沫的討論,已經讓位于AI在多個領域中展現的長期價值證據——包括由AI發現的新藥、優化供應鏈與制造體系,以及依托新技術實現的預防性醫療。

          AI驅動藥物研發的新時代

          根據波士頓咨詢公司(Boston Consulting Group)的一份報告,生成式AI有潛力將早期藥物研發周期縮短25%以上。

          在賽諾菲,我們已經看到這一趨勢帶來的顯著成果。通過將機器學習與數據整合能力結合實驗室研究,我們在一年內發現了10個全新的藥物靶點。AI已不再只是輔助研發工作,而是在主動塑造決策流程。我們在召開藥物開發委員會會議時,會先由AI智能體評估一款候選藥物是否應進入下一臨床試驗階段。關鍵在于,這個智能體并非簡單給出“是”或“否”的答案,而是對每一項決策進行完整的情境分析。它會將該資產的前景與其他在研項目進行對比,并評估其相對于賽諾菲其他資本用途的機會成本。這是一個有力的案例,說明AI讓藥物研發不僅更快速,而且更智能。

          這種轉型并不僅限于實驗室。AI還在解決藥物研發中最頑固的難題之一:臨床試驗招募。AI驅動的患者招募工具,可將臨床試驗入組率提升65%。借助AI,我們能夠通過掃描電子病歷、臨床記錄與化驗結果,自動篩選符合條件的患者,從而更精準地匹配復雜的試驗標準。同時,我們還能實時判斷某個臨床試驗中心的入組進展是否低于預期,并將資源轉向進展更快的中心。過去需要數月才能完成招募的試驗,如今可在數天或數周內找到合適人選。

          除了加速靶點發現與臨床試驗招募流程,AI驅動的工具也在重塑研發的經濟邏輯。通過加快早期藥物發現并生成科學洞見,AI有望將相關成本降低約50%。這些變化將重新定義哪些類型的藥物具備商業可行性。未來一年,尤其是在精準醫療領域,我們可以期待關鍵突破變得更具規模化和可及性。近期多項研究指出,在AI、多組學技術以及前所未有的數據基礎設施支持下,精準醫療正從高度定制化靶向治療,轉向面向大規模人群的普惠醫療模式。

          構建下一代供應鏈與制造體系

          AI識別供應鏈脆弱性的能力幾乎無可匹敵。借助更高水平的可視化與實時追蹤能力,AI系統能夠以前所未有的方式洞察庫存狀況與產品流向。

          在賽諾菲,AI驅動的供應鏈管理已幫助公司規避了3億美元的收入風險,并提前預測到80%的低庫存風險。通過擴大數據獲取范圍、提升跨部門透明度,企業能夠及時作出更明智的決策。其影響是切實可見的:已有68%的供應鏈企業整合了AI以增強可追溯性與透明度,運營效率因此提升22%。未來幾年,隨著 AI進一步融入全球供應網絡,這些效益還將持續加速顯現。

          除了提升供應鏈的可視化與預測能力,AI也正在重塑藥品制造方式。它為制造流程提供端到端支持,包括提高效率、改善產品質量與安全性,以及通過實時監測確保穩定、可靠的產出。根據麥肯錫(McKinsey & Company)的分析,AI驅動的數據分析能夠顯著提高產出率,不僅有助于患者更快獲得關鍵藥物,也能提升制造運營的成本效率與可持續性。

          推進預防性與預測性醫療

          預防醫學的下一個前沿是依托遠程患者監測與數字化工具,實現早期干預。一項涵蓋 1,100余例患者診療案例的研究發現,遠程患者監測可將住院率降低近60%。在慢性病管理領域,可穿戴設備、癥狀追蹤應用以及環境傳感器的結合,正展現出變革性潛力。針對慢性阻塞性肺?。–OPD)患者,一項整合上述工具的數字化項目在預測病情加重方面實現了94%的敏感度與90.4%的特異度,使臨床醫生能夠在危機發生前介入。這類整合型數字治療模式,正在減少脆弱人群的急診就診與住院率。隨著AI加速制藥與醫療行業的進程,我們在更早階段進行發現、預測與干預的能力也將持續提升。

          預防醫學的未來,將由疫苗、治療手段、數據與智能監測的融合所定義。通過將科學創新與AI驅動的洞見相結合,我們有機會推動醫療模式從“被動治療”轉向“主動、持續的防護”。這將帶來更好的治療效果、更低的成本,并最終大規模改變患者生活。

          我們正步入一個由AI驅動企業各項職能的新時代。2026年,制藥行業的AI轉型有望進一步提速,我們將持續推進改變患者命運的藥物研發。隨著AI能力的不斷擴展,我們已經看到討論的重點已經從對“泡沫”的擔憂,轉向了對企業驅動的長期價值的關注。最終留下的,可能不是炒作,而是持續增長與深層變革。(財富中文網)

          本文作者韓保羅自2019年9月起擔任賽諾菲首席執行官。此前,他于2016年至2019年出任諾華制藥首席執行官。在加入諾華之前,曾就職于阿斯利康,擔任多個高管職務,包括阿斯利康美國總裁及北美區執行副總裁。職業生涯早期,他在葛蘭素史克英國公司以及賽諾菲-信達博英國公司擔任銷售和市場營銷崗位。

          Fortune.com上發表的評論文章中表達的觀點,僅代表作者本人的觀點,不代表《財富》雜志的觀點和立場。

          譯者:劉進龍

          審校:汪皓

          At Davos this year, AI was a key pillar of discussion. Increasingly, people recognize the impact it is already having on innovation and growth. I believe that we will see in the months ahead companies in all sectors proving that AI is not a speculative moment in time but a durable engine of transformation that’s fundamentally reshaping how we work.

          At Sanofi, AI has shifted from experimentation to becoming a vital part of our infrastructure. It now powers our R&D decisions, our supply chain and manufacturing processes, and most importantly how we discover and develop medicines. All businesses that have implemented AI in an impactful way face challenges, such as skills gaps and uncertainty, but you move beyond that by embedding AI deeply into teams and systems. This enables AI to become a key, reliable source of sustained productivity and innovation.

          The critical factor in 2026 and beyond will be enterprise-scale implementation, shifting from experimenting with AI to operationalizing it at the core of how companies work. This will be the tipping point where AI speculation ends, and where it becomes a fundamental driver of growth. As more organizations reach this stage, debates about bubbles have already given way to evidence of durable, long-term value in areas including new drugs discovered by AI, optimized supply chain and manufacturing and preventative medicine powered by new technologies.

          The New Era of AI-Driven Drug Development

          According to a Boston Consulting Group report, generative AI has the potential to accelerate early-stage drug breakthroughs, reducing timelines by 25% or more.

          At Sanofi, we are already seeing this materialize with dramatic results. Combining machine learning and data integration with lab research has helped us discover 10 completely news drug targets in just one year. AI is no longer just assisting R&D efforts, it is actively shaping decision-making. Our drug development committee meetings begin with an AI agent’s assessment of whether a drug should advance to the next trial phase. Crucially, the agent does not simply give a yes or no answer but fully contextualizes each decision. It compares the asset’s prospects against others in development and assesses its opportunity cost relative to alternative uses of Sanofi’s capital. This is a powerful example of how AI is making drug development not only faster, but smarter.

          This transformation doesn’t stop in the lab. AI is also addressing one of the most persistent obstacles in drug development: clinical trial recruitment. AI-powered patient recruitment tools improve clinical trial enrollment rates by 65%. Through AI we can now automate patient eligibility through scanning electronic health records, clinical notes and lab results. This enables higher accuracy in matching patients to complex criteria in trials. We can also determine in real time if a clinical trial site is not enrolling as expected and move our efforts to sites that are progressing more rapidly. Trials that once required months to recruit now find the right patients in days or weeks.

          Beyond accelerated target discovery and clinical trial recruitment processes, AI-driven tools are transforming the economics of R&D. Its accelerating early-stage drug discovery and generating scientific insights that can reduce costs by an estimated 50%. These shifts are poised to reshape what kinds of medicines become viable. In the year ahead, we can expect key breakthroughs, particularly in precision medicine, to become more scalable and accessible. Recent reviews underscore that thanks to AI, multi-omics and an unprecedented data infrastructure precision medicine is moving from bespoke targeting to large-scale, population-level care models.

          Building the Next Generation of Supply Chains & Manufacturing

          AI’s ability to detect vulnerabilities in supply chains is unparalleled. Through enhanced visibility and real-time tracking, AI systems provide unprecedented insights into inventory levels and product movement.

          At Sanofi, AI-driven supply chain management has enabled the company to avoid $300 million in revenue risk and predict 80% of low inventory risks before they occur. By expanding access to data and increasing transparency across functions, organizations can make better informed decisions in a timely manner. The impact is tangible: 68% of supply chain organizations have already integrated AI to enhance traceability and visibility, resulting in a substantial 22% increase in operational efficiency. These gains will only accelerate over the next few years as AI becomes further embedded in global supply networks.

          Beyond visibility and forecasting in supply chain operations, AI is reshaping the way we approach the manufacturing of medicines. AI is providing end-to-end support in manufacturing through enhancing efficiency, product quality and safety and enabling real-time monitoring that ensures consistent, reliable output. According to McKinsey, AI-driven analytics can significantly maximize yield which not only ensures patients are receiving critical medicines faster but also improves the cost and sustainability of manufacturing operations.

          Advancing Preventative and Predictive Care

          The next frontier in prevention is early intervention supported by remote patient monitoring and digital tools. One study of more than 1,100-plus patient encounters found that remote patient monitoring cut hospitalizations by nearly 60%. For chronic diseases, the combination of wearables, symptom-tracking apps and environmental sensors is proving to be transformative. In COPD patients, a digital program integrating these tools achieved 94% sensitivity and 90.4% specificity in predicting exacerbations enabling clinicians to intervene before crises occur. These types of integrated digital therapeutic models are reducing emergency visits and admissions for vulnerable populations. As AI accelerates timelines across the pharma and healthcare industry, our ability to discover, predict and intervene earlier will only expand.

          The future of prevention will be defined by the convergence of vaccines, therapeutics, data and intelligent monitoring. By pairing scientific innovation with AI-driven insights, we have the opportunity to shift the healthcare approach from reactive treatment to proactive, continuous protection. The result will be improved outcomes, reduced costs and ultimately transformation of patient lives at scale.

          We are in a new era powered by AI across business functions. 2026 promises accelerated momentum of AI-powered transformation in the pharmaceutical industry as we continue to pursue the discovery of life-changing medicines for patients. As AI capabilities continue to scale, we’ve already seen the conversation shift away from concerns about a bubble and toward the evidence of durable, enterprise-driven value. What is likely to remain is not hype but sustained growth and meaningful transformation.

          Paul Hudson has been CEO of Sanofi since September 2019. Previously, he was CEO of Novartis Pharmaceuticals from 2016 to 2019. Prior to Novartis, he worked for AstraZeneca, where he held several increasingly senior positions and served as president, AstraZeneca US and executive vice president, North America. He began his career in sales and marketing roles at GlaxoSmithKline UK and Sanofi-Synth?labo UK.

          The opinions expressed in Fortune.com commentary pieces are solely the views of their authors and do not necessarily reflect the opinions and beliefs of Fortune.

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